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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Arch Toxicol. 2019 Apr 21;93(6):1665–1677. doi: 10.1007/s00204-019-02449-y

Figure 7.

Figure 7.

Top Panels: Effect of TBT exposure on mRNA expression (mean ± SEM) of cholesterol transporters (ABCA1 and StAR) in pre-luteinized (A) and luteinized (B) human primary ovarian theca cells exposed to 1 ng/ml TBT (gray bars), 10 ng/ml TBT (closed bars) or vehicle (control group; open bars). Bottom Panels: Effect of TBT exposure on ABCA1 and StAR mRNA expression (mean ± SEM) in pre-luteinized human primary theca cells exposed to 10 ng/ml TBT (light gray bars), RXR antagonist (UVI3003; 8 μM; dark gray), the combination of TBT (10 ng/ml) and RXR antagonist (8 μM), or vehicle (control group; open bars). Asterisks denote differences among treatments (P < 0.05). N=3 primary cultured cell lines per group.