TABLE 1.

Patient demographics and mutational load

ID	Sex	Race	Age	Smoking history	Alcohol history	Prior treatment	Cancer site	HPV status	Final pTNM stage	Responder status	SNV	Missense mutations
2	Men	White	51	Yes	Yes	None	Oral cavity	Negative	T4AN0MX	Yes	1285	118
11	Women	White	58	No	Yes	None	Oropharynx	Not tested	T2N2BMX	Yes	1363	148
16	Women	White	51	Yes	Yes	None	Oropharynx	Negative	T2N)MX	Yes	1486	194
22	Men	White	62	Yes	Yes	None	Oral cavity	Not tested	T2N0MX	Yes	1248	107
23	Men	White	54	Yes	Yes	None	Oral cavity	Not tested	T2N2CMX	Yes	1388	149
24	Men	White	62	Yes	Yes	None	Oral cavity	Not tested	T2N1MX	Yes	1375	177
27	Women	White	47	Yes	Yes	None	Oral cavity	Not tested	T4AN1MX	Yes	1340	136
29	Men	White	64	Yes	Yes	None	Oropharynx	Positive	T1N1MX	Yes	2851	366
36	Men	White	69	Yes	Yes	None	Oral cavity	Negative	T4AN0MX	Yes	1566	148
37	Men	White	64	Yes	Yes	None	Larynx	Not tested	T4AN1MX	Yes	2297	340
39	Men	White	65	Yes	Yes	None	Oral cavity	Not tested	T2N0MX	Yes	1467	185
6	Men	White	69	Yes	Yes	None	Oropharynx	Positive	T3N2BMX	No	1589	206
10	Women	White	40	No	No	None	Oropharynx	Negative	T2N2BMX	No	1384	174
13	Men	White	60	Yes	No	None	Oropharynx	Positive	T2N1MX	No	1568	229
14	Men	African American	55	Yes	Yes	None	Larynx	Not tested	T3N1MX	No	1814	238
15	Men	White	64	Yes	Yes	None	Oral cavity	Not tested	T1N1MX	No	1313	134
18	Men	White	52	Yes	Yes	None	Oropharynx	Negative	T2N)MX	No	1550	181
19	Men	White	59	No	Yes	None	Oropharynx	Positive	T2N2AMX	No	5489	1635
20	Men	White	64	Yes	Yes	None	Oropharynx	Positive	T2N2BMX	No	2360	476
21	Men	White	51	No	Yes	None	Oropharynx	Positive	T1N2BMX	No	1583	224

Abbreviations: SNV, Single Nucleotide Variant; HPV, Human Papilloma Virus.