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. Author manuscript; available in PMC: 2020 Jul 12.
Published in final edited form as: ACS Infect Dis. 2019 May 1;5(7):1231–1238. doi: 10.1021/acsinfecdis.9b00071

Figure 2. Structure–activity relationships (SARs) for inhibition of bacterial growth.

Figure 2.

Three series of analogues were synthesized to explore SAR associated with the substituent on the phenyl ring (SAR1), the sulfonamide linker (SAR2), and the oxaborole ring (SAR3). MIC values (μg/mL) against MRSA (ATCC BAA-1762) were determined by broth microdilution; values of < 10 μg/mL are indicated in red.