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Gene distribution of likely-somatic variants (N=775).
| Gene | Frequency | Percent |
|---|---|---|
| TP53 | 224 | 28.9 |
| CHEK2 | 223 | 28.8 |
| ATM | 162 | 20.9 |
| BRCA2 | 23 | 3.0 |
| APC | 21 | 2.7 |
| BRCA1 | 12 | 1.5 |
| NBN | 11 | 1.4 |
| MLH1 | 10 | 1.3 |
| PMS2 | 10 | 1.3 |
| CDH1 | 9 | 1.2 |
| BRIP1 | 8 | 1.0 |
| PALB2 | 8 | 1.0 |
| MSH6 | 6 | 0.8 |
| BARD1 | 5 | 0.6 |
| PTEN | 5 | 0.6 |
| SMAD4 | 5 | 0.6 |
| CDK4 | 4 | 0.5 |
| RAD51D | 4 | 0.5 |
| STK11 | 4 | 0.5 |
| BMPR1A | 3 | 0.4 |
| CDKN2A (p14ARF) | 3 | 0.4 |
| MUTYH | 3 | 0.4 |
| POLD1 | 3 | 0.4 |
| RAD51C | 3 | 0.4 |
| CDKN2A (p16INK4a) | 2 | 0.3 |
| MSH2 | 2 | 0.3 |
| POLE | 2 | 0.3 |
| TOTAL | 775 | - |
