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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2019 Jan 11;192:105283. doi: 10.1016/j.jsbmb.2019.01.001

Figure 5.

Figure 5.

Lead N-naphthylaminobenzoates display competitive enzyme inhibition for the oxidation of S-tetralol and reduction of 4-Androstene-3,17-dione catalyzed by AKR1C3. Panels (A-C) competitive inhibition of S-tetralol oxidation by compounds 1, 3 and 4, respectively. Panels (D-F) competitive inhibition of 4-androstene-3,17-dione reduction by compounds 1, 3 and 4, respectively.