Table 1.
Identification of infection-associated microRNAs using Taqman Low Density Arrays.
| microRNA | Gram+ infection | Gram− infection |
|---|---|---|
| miR-223 | +6.9 | +13.1 |
| miR-139-5p | +3.5 | +8.3 |
| miR-197 | +2.2 | +7.9 |
| miR-27a | +4.8 | +1.2 |
| miR-21 | −2.6 | −1.4 |
| miR-31 | −1.9 | −2.1 |
| miR-199a-3p | −2.8 | −12.3 |
| miR-100 | −3.7 | −16.7 |
| miR-99a | −1.3 | −55.6 |
10 effluent samples each were pooled from stable non-infected individuals and from patients presenting with acute peritonitis that was subsequently confirmed as coagulase-negative Staphylococcus (Gram+) or E. coli infections (Gram−), and analysed using TLDA. microRNA levels in each group were normalised to the global expression levels across the plate, and are shown as relative values compared to levels in stable individuals as reference (set to 1.0). Only microRNAs that could be detected in all three groups were included in this analysis.