Table 1.
Cementum-PDL formation on implant.
| Cell sourse | Method of cell transplantation | Type of Implant | Implant surface modification | New cementum-PDL like tissue | Experimental animal | Healing period | Year | Reference |
|---|---|---|---|---|---|---|---|---|
| Retained tooth root | - | Hollow-cylinder Ti implant | Plasma-sprayed | Yes | Monkey | 12 months | 1990 | # [22] |
| Retained tooth root | - | Self-tapping screw tiype Ti implant | - | Yes | Monkey | 3 months | 1993 | # [23] |
| Tooth root | - | Screw type Ti implant | HA | Yes | Dog | 3 months | 2000 | # [24] |
| PDL cells | Direct cell culture on implant | Screw type Ti implant | - | Yes | Dog | 3 months | 2000 | # [25] |
| Retained tooth root | - | - | - | only cementum | Human (case report) | 1 year | 2002 | # [26] |
| PDL tissue | - | Self-tapping cylinder type Ti implant | Plasma sprayed, Sandblasting Large-grit acid-etching | Yes | Dog | 4 months | 2005 | # [27] |
| Retained PDL in extracted socket | - | Custam made Ti implant | - | Yes | Rat | 4 weeks | 2005 | # [28] |
| Contacted tooth with Implant by orthodontic movement | - | Ti implant | HA | Yes | Dog | 8 weeks | 2005 | # [29] |
| PDL cells | Direct cell culture on implant in bioreactor | Cone-shaped cylinder Ti pin | HA | Yes | Dog | 20 weeks | 2010 | # [30] |
| Retained root fragment in contact with implant (SST) | - | Ti implant | - | Yes | Dog | 4 months | 2010 | # [31] |
| PDL cells | Matrigel as a scafold | Custam made Ti implant | Sandblasting Large-grit acid-etching | Yes | Rat | 12 weeks | 2011 | # [32] |
| Remained PDL in extracted socket | - | Custam made Ti implant | HA | only PDL | Rat | 4 weeks | 2012 | # [33] |
| Dental follicle taken from tooth germ | Wrapping of implant with dental follicle | Custam made Ti implant | HA | Yes | Mouse | 30 days | 2014 | # [34] |
| PDL cells + HUVEC + cementoblasts + ERM cells | Cell Sheet | Custam made Ti implant | HA | Yes | Mouse | 8 weeks | 2017 | # [35] |
| PDL cells | Cell Sheet | Cylinder type Ti implant | Acid etching, blasting, calcium phosphate coating | Yes | Dog | 11 weeks | 2018 | # [13] |
| Retained root fragment in contact with implant (SST) | - | Ti implant | - | No | Human (Failed implant) | About 2 years | 2018 | # [36] |
PDL: periodontal ligament, HUVEC: human umbilical vein endothelial cell, ERM: epithelial cell rests of Malassez, HA: hydroxyapatite, Ti: titanium, SST: Socket Shield Technique.