Figure 5.

Vatiamide pathway promiscuous dd interactions. A) VatM and VatP Cdd alignment. B) VatN/Q/S Ndd aligned with characterized dds. Key interaction points in red triangles. C) Depiction of “docking”; electrostatic and steric interactions of residues in blue dots.[10,11] D) Vat pathway promiscuity: T; thiolase, Cond; condensation domain.