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. 2019 Jul 12;16:30. doi: 10.1186/s12989-019-0314-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — PSC-Fe₂O₃ induced ·OH production by peroxidase-like activities. a Intracellular ROS of HUVEC. b HO-1 gene expression of HUVEC. c Extracellular ROS of HUVEC. d Extracellular H₂O₂. e PSC-Fe₂O₃ catalyzed H₂O₂ into ·OH in a concentration dependent manner. f The ESR spectrum of DMPO / ·OH adduct. Data are mean ± SD, n = 3, one-way ANOVA with Dunnett’s multiple comparisons test, *p < 0.05, **p < 0.01, significant compared to control