Table 1.
Distribution of ESBL factors, antibiotic resistance and VF genes in MDR UPEC
| Numbers and percentagesof isolates and their respective traits (n = 155) | ||||||
|---|---|---|---|---|---|---|
| Resistance traits | Total Isolates (n = 155)n (%) | Group A (n = 8)n(%) |
Group B1 (n = 12) n(%) |
Group B2 (n = 92) n(%) |
Group D (n = 43)n(%) |
p value |
| ESBL phenotypes | 65(42) | 1(13) | 3(25) | 36(39) | 25(58) | 0.0268 |
| blaCTX-M-15 | 57(37) | 1(13) | 3(25) | 32(35) | 21(49) | 0.1333 |
| blaTEM | 23(15) | 1(13) | 3(25) | 13(14) | 6(14) | 0.7823 |
| blaSHV | 6(4) | 00 | 00 | 3(3) | 3(7) | 0.0907 |
| blaOXA | 10(6) | 00 | 1(8) | 4(4) | 5(12) | 0.3610 |
| blaPSE | 1(0.6) | 00 | 00 | 1(1) | 00 | 0.8783 |
| Piperacillin tazobactam | 7(5) | 00 | 1(8) | 4(4) | 2(5) | 0.8514 |
| Ceftazidime | 96(62) | 3(38) | 7(58) | 54(59) | 32(74) | 0.1483 |
| Cefotaxime | 101(65) | 3(38) | 7(58) | 59(64) | 32(74) | 0.2028 |
| Ceftriaxone | 99(64) | 3(38) | 8(67) | 59(64) | 29(67) | 0.4001 |
| Ciprofloxacin | 95(61) | 6(75) | 7(58) | 56(90) | 26(60) | 0.4001 |
| Levofloxacin | 97(63) | 7(88) | 8(67) | 56(90) | 26(60) | 0.4929 |
| Amikacin | 7(5) | 1(13) | 00 | 5(5) | 1(2) | 0.4920 |
| Gentamicin | 47(30) | 4(50) | 6(50) | 24(26) | 13(30) | 0.2171 |
| Amoxicillin-clavulanic acid | 111(72) | 5(63) | 7(58) | 66(72) | 26(60) | 0.5224 |
| Trimethoprim sulfonamides | 130(84) | 7(88) | 11(92) | 77(84) | 35(81) | 0.8461 |
| Nitrofurantoin | 9(6) | 1(13) | 1(8) | 6(7) | 1(2) | 0.6075 |
| Fosfomycin | 15(10) | 1(13) | 2(17) | 8(9) | 4(9) | 0.8370 |
| fimH | 155 (100) | 8 (100) | 12 (100) | 92 (100) | 43 (100) | > 0.9999 |
| papA | 20 (13) | 1 (13) | 1 (8) | 12 (13) | 6 (14) | 0.9659 |
| papC | 75 (48) | 2 (25) | 8 (67) | 43 (47) | 22 (51) | 0.3092 |
| papEF | 37 (24) | 0 | 6 (50) | 19 (21) | 12 (28) | 0.0476 |
| papGI | 6 (4) | 0 | 0 | 3 (3) | 3 (7) | 0.5699 |
| papGII | 70 (45) | 2 (25) | 7 (58) | 37 (40) | 24 (53) | 0.1695 |
| papGIII | 6 (4) | 0 | 0 | 4 (4) | 2 (5) | 0.8177 |
| sfa/foc | 20 (13) | 2 (25) | 1 (8) | 13 (14) | 4 (9) | 0.5968 |
| Afa | 15 (10) | 0 | 1 (8) | 10 (11) | 4 (9) | 0.7919 |
| bmaE | 2 (1) | 0 | 1 (8) | 1 (1) | 0 | 0.1466 |
| fyuA | 37 (24) | 1 (13) | 2 (17) | 21 (23) | 13 (30) | 0.5882 |
| iutA | 86 (55) | 5 (63) | 5 (42) | 52 (57) | 24 (56) | 0.7701 |
| feoB | 76 (49) | 3 (38) | 6 (50) | 40 (43) | 27 (63) | 0.1852 |
| kpsmtII | 40 (26) | 0 | 4 (33) | 21 (23) | 15 (35) | 0.1438 |
| kpsmtIII | 4 (3) | 0 | 1 (8) | 3 (3) | 0 | 0.3765 |
| Usp | 22 (14) | 2 (25) | 2 (17) | 14 (15) | 4 (9) | 0.6256 |
| hlyA | 18 (12) | 1 (13) | 3 (25) | 6 (7) | 8 (19) | 0.0908 |
| cdtB | 11 (7) | 0 | 3 (25) | 6 (7) | 2 (5) | 0.0758 |
Distribution of resistance and virulence traits among different phylogroups of uropathogenic E. coli (N = 155). The p values were calculated by comparing different traits among phylogroups