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. 2019 Jul 12;20:581. doi: 10.1186/s12864-019-5917-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Heatmap depicting the top 35 functionally annotated extracellularly secreted protein (ESP) encoding genes upregulated (Orange) in the pedal disc of E. pallida. Z-scores are representative of centred gene expression values (Log₂). WA_1 – WA_4 = Whole Animal; AM_1 – AM_3 = Amputated animals (pedal disc amputated). * = Non-classically secreted; ** = Classically secreted