Table 2.
Top 35 ab initio predicted extracellular secreted proteins which received a meaningful functional annotation. Mode = Secretory mode: C = Classical secretory pathway (Predicted by SignalP5.0); NC = Non-classical secretory pathway (Predicted by SecretomeP2.0). FC = Log2 fold change of gene expression
| Aipgene | Mode | Annotation | FC | Protein superfamily domain (s) |
|---|---|---|---|---|
| 2358 | NC | Deleted in malignant brain tumors 1 protein | 6.47 | 1 Spermadhesin, CUB domain,2 SRCR-like |
| 7203 | NC | Coagulation factor XI | 4.67 | 1 Trypsin-like serine proteases |
| 5888 | C | Chymotrypsinogen B | 4.59 | 1 Trypsin-like serine proteases |
| 5529 | C | Collagen triple helix repeat-containing protein 1 | 4.20 | – |
| 25995 | C | Heme-binding protein 2 | 3.82 | 1 Probable bacterial effector-binding domain |
| 24564 | C | Short-chain collagen C4 (Fragment) | 3.68 | – |
| 11959 | C | Matrix metalloproteinase-24 | 3.51 | 1 PGBD-like |
| 23885 | NC | Nematocyte expressed protein 6 | 3.36 | 1 Metalloproteases (“zincins”), catalytic domain |
| 28234 | C | Blastula protease 10 | 3.35 | 1 Metalloproteases (“zincins”), catalytic domain |
| 26183 | C | Dorsal-ventral patterning tolloid-like protein 1 | 3.26 | 2 Spermadhesin, CUB domain |
| 8891 | C | EGF-like repeat and discoidin I-like domain-containing protein 3 | 3.14 | 5 Galactose-binding domain-like |
| 7095 | NC | Deleted in malignant brain tumors 1 protein | 3.04 | – |
| 4050 | C | Cubilin | 2.75 | 2 Concanavalin A-like lectins/glucanases,4 Spermadhesin, CUB domain |
| 17639 | C | Semaphorin-5B | 2.68 | 3 CalX-like,6 TSP-1 type 1 repeat |
| 14619 | NC | Golgi-associated plant pathogenesis-related protein 1 | 2.53 | 1 PR-1-like |
| 27786 | C | Agrin | 2.50 | 10 Kazal-type serine protease inhibitors |
| 1814 | C | Nephronectin | 2.47 | 2 Growth factor receptor domain |
| 3178 | C | Toxin AvTX-60A | 2.45 | – |
| 18607 | C | Golgi-associated plant pathogenesis-related protein 1 | 2.44 | 1 PR-1-like |
| 19786 | C | Inactive pancreatic lipase-related protein 1 | 2.37 | 1 alpha/beta-Hydrolases,1 Lipase/lipooxygenase domain (PLAT/LH2 domain) |
| 17513 | NC | Neuronal pentraxin-2 | 2.34 | 1 Concanavalin A-like lectins/glucanases,1 Integrin alpha N-terminal domain |
| 894 | C | Protransforming growth factor alpha | 2.33 | 1 EGF/Laminin |
| 4815 | NC | Hemicentin-1 | 2.33 | 4 TSP-1 type 1 repeat |
| 28816 | C | Blastula protease 10 | 2.31 | 1 Concanavalin A-like lectins/glucanases,1 Metalloproteases (“zincins”), catalytic domain,1 TSP-1 type 1 repeat |
| 6291 | NC | Golgi-associated plant pathogenesis-related protein 1 | 2.29 | 1 PR-1-like |
| 14545 | NC | Venom prothrombin activator oscutarin-C non-catalytic subunit | 2.25 | 1 Family A G protein-coupled receptor-like,1 Galactose-binding domain-like |
| 17088 | C | Short-chain collagen C4 (Fragment) | 2.24 | – |
| 7224 | NC | Plasma kallikrein | 2.23 | 1 Trypsin-like serine proteases |
| 6481 | C | Three prime repair exonuclease 2 | 2.23 | 1 Ribonuclease H-like |
| 13236 | C | Collagen triple helix repeat-containing protein 1 | 2.22 | – |
| 10560 | C | Chondroitin proteoglycan 2 | 2.17 | 11 Invertebrate chitin-binding proteins |
| 16517 | C | Disintegrin and metalloproteinase domain-containing protein 10 | 2.13 | – |
| 20335 | C | Collagen alpha-1(XXVII) chain | 2.13 | – |
| 25531 | NC | Fibronectin | 2.13 | 1 Kringle-like |
| 19685 | C | Expansin-YoaJ | 2.12 | 1 Barwin-like endoglucanases,1 Invertebrate chitin-binding proteins,1 PHL pollen allergen |