Table 2.

Results of univariable and multivariabe Cox regression analyses

Variable		All-cause mortality			Cardiovascular mortality
		Hazard ratio	CI	P-value	Hazard ratio	CI	P-value
Univariable	n
Diabetes mellitus	335	1.14	1.06–1.22	< 0.001	1.14	1.08–1.22	< 0.001
Per increase of 1% of hba1c	1065	1.23	1.15–1.32	< 0.001	1.30	1.20–1.41	< 0.001
Carotid stenosis ≥ 50%	374	1.67	1.40–1.97	< 0.001	1.70	1.39–2.08	< 0.001
Combined model
Carotid stenosis < 50%; Ø DMa	522	Ref
Carotid stenosis ≥ 50%; Ø DM	276	1.65	1.33–2.06	< 0.001	1.71	1.30–2.25	< 0.001
Carotid stenosis < 50%; DM	166	1.86	1.48–2.34	< 0.001	2.13	1.61–2.81	< 0.001
Carotid stenosis ≥ 50%; DM	101	3.23	2.53–4.13	< 0.001	3.67	2.73–4.94	< 0.001
Multivariable
Diabetes mellitus	335	1.14	1.06–1.22	< 0.001	1.14	1.08–1.22	< 0.001
Per increase of 1% of hba1c	1065	1.21	1.12–1.32	< 0.001	1.30	1.20–1.43	< 0.001
Carotid stenosis ≥ 50%	374	1.28	1.30	0.004	1.28	1.03–1.60	0.025
Combined model
Carotid stenosis < 50%; Ø DMa	522	Ref
Carotid stenosis ≥ 50%; Ø DM	276	1.27	1.01–1.59	0.040	1.26	0.96–1.64	0.072
Carotid stenosis < 50%; DM	166	1.56	1.22–1.99	< 0.001	1.78	1.33–2.39	< 0.001
Carotid stenosis ≥ 50%; DM	101	2.22	1.71–2.99	< 0.001	2.35	1.71–3.24	< 0.001

CI confidence interval, HR hazard ratio, hsCRP high sensitivity C-reactive protein

^aReference category; adjusted for age, sex, body mass index, hypertension smoking, history of peripheral artery disease, history of stroke history of myocardial infarction, low-density lipoprotein cholesterol levels, triglyceride levels, statin treatment, serum creatinine, hsCRP