Table 5.
Meta-Analyses of Human Epidemiologic Studies Dealing With Cancer and Vitamin D Status
| Cancer |
Author | No. of Studies/Analysis | Pooled RRs | |
|---|---|---|---|---|
| Colorectal | Ma et al. (310) | 9 | 0.88 (0.8–0.96) Vitamin D intake | |
| 0.67 (0.54–0.80) 25OHD levels | ||||
| Yin et al. (311) | 10 | 0.82 (0.69–0.97) 25OHD levels | ||
| Breast | Chen et al. (312) | 11 | 0.91 (0.85–0.97) Vitamin D intake | |
| 8 | 0.55 (0.38–0.80) 25OHD levels | |||
| 0.83 (0.79–0.87) Case control (5) | ||||
| Gandini et al. (308) | 10 | 25OHD levels | ||
| 0.97 (0.92–1.03) Prospective (5) | ||||
| Prostate | Gandini et al. (308) | 11 | 0.99 (0.95–1.03) 25OHD levels | |
| Gilbert et al. (313) | 13 | 1.14 (0.99–1.31) Vitamin D intake | ||
| 14 | 1.04 (0.99–1.10) 25OHD levels | |||
There was inconsistency of the association between vitamin D status and breast or prostate cancer, but a consistent association with colorectal cancer.