Table 2.
Histomolecular features of the cohort, together with cystathionine and 2HG concentrations from edited MRS.
| Subject # |
Histological diagnosis | IDH status | 1p/19q codel | [Cystathionine, mM] (CRLB, %) |
[2HG, mM] (CRLB, %) |
VOI size, mL/ Tumor in VOI, % |
|---|---|---|---|---|---|---|
| S01 | Oligodendroglioma grade II | IDH1 R-132H | Yes | 2.4 (20) | 4.9 (10) | 8/90 |
| S02 | Oligodendroglioma grade II | IDH1 R-132H | Yes | 3.8 (11) | 1.7 (25) | 6.4/97 |
| S03 | Oligodendroglioma grade II | IDH1 R-132H | Yes | 2.0 (21) | 1.9 (22) | 8/94 |
| S04 | Oligodendroglioma grade II | IDH1 R-132H | Yes | 2.0 (14) | 1.7 (17) | 7.2/89 |
| S05 | Oligodendroglioma grade II | IDH1 R-132H | Yes | 0.8 (57) | 0.9 (57) | 12/75 |
| S06 | Oligodendroglioma grade II | IDH1 R-132H | Yes | 0.2 (221) | 1.0 (38) | 10/50 |
| S07 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 4.0 (7) | 2.6 (11) | 8/91 |
| S08 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 3.2 (11) | 2.7 (11) | 20/87 |
| S09 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 2.0 (26) | 2.2 (25) | 8/97 |
| S10 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 1.5 (32) | 9.6 (6) | 9.7/88 |
| S11 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 3.9 (11) | 3.1 (14) | 8/100 |
| S12 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 3.7 (8) | 2.0 (16) | 10.6/100 |
| S13 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 4.1 (14) | 1.2 (45) | 8/98 |
| S14 | Anaplastic oligodendroglioma grade III | IDH1 R-132C | Yes | 2.9 (16) | 1.1 (38) | 8/45 |
| S15 | Anaplastic oligodendroglioma grade III | IDH1 R-132H | Yes | 0.5 (79) | 1.2 (36) | 9/91 |