Table 2.

Sensitivity analysis for depression by obesity-related metabolic status

	Metabolic Status	N	OR	95% CI
Entire sample
	MHN	9,386	Ref
	MHO	2,294	1.51	1.30–1.74
	MUN	2,951	1.39	1.18–1.64
	MUO	3,394	2.31	2.02–2.67
Sex
Men	MHN	4,832	Ref
	MHO	1,154	1.25	0.97–1.69
	MUN	1,230	1.07	0.82–1.40
	MUO	1,531	1.63	1.31–2.10
Women	MHN	4,554	Ref
	MHO	1.140	1.71	1.42–2.09
	MUN	1,721	1.62	1.30–2.04
	MUO	1,863	2.83	2.40–3.30
P value for interaction			<0.001
Age
<50 yrs	MHN	5,869	Ref
	MHO	422	1.22	0.85–1.77
	MUN	2,008	1.44	1.10–1.60
	MUO	1,183	2.09	1.65–2.55
≥50 yrs	MHN	3,487	Ref
	MHO	1,872	1.31	1.08–1.62
	MUN	943	1.49	1.14–1.98
	MUO	2,211	2.16	1.78–2.55
P value for interaction			0.41
Race/ethnicity
White	MHN	3,994	Ref
	MHO	1,053	1.66	1.33–2.08
	MUN	1,083	1.19	0.92–1.53
	MUO	1,490	2.23	1.84–2.69
African American	MHN	1,754	Ref
	MHO	394	1.03	0.77–1.03
	MUN	873	1.47	0.81–2.39
	MUO	873	1.57	1.20–2.06
Hispanic	MHN	2,113	Ref
	MHO	532	1.61	1.22–2.13
	MUN	802	1.76	1.28–2.40
	MUO	874	2.60	2.04–3.32
P value for interaction			0.71
MetS defined without waist circumference
	MHN	8049	Ref
	MHO	3631	1.57	1.36–1.82
	MUN	2823	1.53	1.31–1.80
	MUO	3522	2.57	2.24–2.94

All models are adjusted for demographic characteristics (age, sex, race/ethnicity, education, marital status, history of smoking, physical activity, and household income) comorbidities (coronary artery disease, congestive heart disease, stroke, pulmonary disease, chronic kidney disease, liver disease, and malignancy) and medication use (antidepressants and statins). Bold indicates estimates that are significantly different from the reference at the p < 0.05 level. OR = odds ratio; CI = confidence interval; Ref = reference; MHN = metabolically healthy normal weight; MUN = metabolically unhealthy normal weight; MHO = metabolically healthy obesity; MUO = metabolically unhealthy obesity.