Table 2.
Multiple Regression Illustrating Relationships Between Psychosocial Factors and QoL
| QoL (FACT-G) |
|||||
|---|---|---|---|---|---|
| Unstandardized |
Standardized |
||||
| Variable | B | SE | (95% CI) | β | P Value |
| Anxiety (HADS) | –7.10 | 0.22 | (–1.14 to –0.29) | –0.18 | .001a |
| Depressive symptoms (HADS) | –1.45 | 0.33 | (–2.11 to –0.79) | –0.30 | <.001a |
| Fatigue severity (BFI) | –0.59 | 0.53 | (–1.63 to 0.45) | –0.09 | .262 |
| Perceived social support (MSPSS) | 2.09 | 0.67 | (0.77–3.42) | 0.13 | .002a |
| Satisfaction with treatment & providers (FACIT-TS-PS) | 0.17 | 0.08 | (0.02–0.32) | 0.09 | .027a |
| Symptom severity (MDASI) | –0.18 | 0.71 | (–1.59 to 1.22) | –0.02 | .797 |
| Symptom interference (MDASI) | –2.30 | 0.57 | (–3.42 to –1.17) | –0.32 | <.001a |
| ECOG performance status | –2.09 | 1.23 | (–4.52 to 0.34) | –0.07 | .091 |
| Number of months on oral chemotherapy | –0.01 | 0.03 | (–0.06 to 0.05) | –0.01 | .848 |
| Number of other medications | –0.04 | 0.17 | (–0.37 to 0.28) | –0.01 | .790 |
| Total model: adjusted R2=0.77; F[10, 146]=50.53; P<.001 | |||||
Abbreviations: BFI, Brief Fatigue Inventory (range, 0–10); FACIT-TS-PS, Functional Assessment of Chronic Illness Therapy - Treatment Satisfaction - Patient Satisfaction (range, 0–63); FACT-G, Functional Assessment of Cancer Therapy–General (range, 0–108); HADS, Hospital Anxiety and Depression Scale (range, 0–21); MDASI, MD Anderson Symptom Inventory (range, 0–10); MSPSS, Multidimensional Scale of Perceived Social Support (range, 1–7); QoL, quality of life.
a
P<.05.