Skip to main content
. Author manuscript; available in PMC: 2019 Jul 14.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Apr 4;499(3):556–562. doi: 10.1016/j.bbrc.2018.03.189

Fig. 3.

Fig. 3.

Mechanism of inhibition study on compound 4 relative to GTP shows an effect on both Vmax and KM, indicating an uncompetitive mode of binding. Analogous results were obtained with other active 1H-pyrrole-2-carboxamide compounds. Best-fit values were generated with GraphPad Prism 6.0.