Preparation |
Obtain detailed medical history, stage in transplantation, hospital course and complications from the primary HSCT team
Review the electronic medical records including both pertinent inpatient and outpatient medical records
Review social work records
Review any psychiatric records (including for prior psychiatric history and psychiatric medications) if available
Review chemotherapeutic regimens used in the conditioning stage and/or radiation
Review inpatient medications
Inquire about behavioral issues and deficits in engagement with care from inpatient nursing team
Review laboratory results
Review brain imaging results
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Patient Interview |
Obtain a comprehensive history of both physical and psychiatric symptoms
Inquire about pain symptoms
Determine psychiatric history including prior psychiatric treatment and medications
Conduct a safety assessment
Gather social history including the nature of social supports, religion and spirituality factors
Conduct mental status exam including a comprehensive cognitive screening instrument, e.g., MoCA53
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Differential Diagnoses |
Consider common medical etiologies of neuropsychiatric symptoms e.g., rare infections [including from viruses (Herpes viruses like Human Herpes Virus 6, Epstein Barr viruses), parasites (toxoplasmosis), fungus (mucormycosis)], thyroid disease, and nutritional deficiencies in addition to psychiatric diagnoses
Explore potential symptoms related to existential distress
Elicit difficulty coping and adjustment issues that do not necessarily qualify for an adjustment disorder
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Treatment/Interventions |
Pharmacological interventions including psychiatric medications
Non-pharmacological interventions e.g., cognitive behavioral therapy
Spiritual care services
Social work support
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Considerations for liaison with care team |
Awareness of the complex nature of the inpatient care team including medical house staff who may rotate quite often over the course of a transplant admission
Familiarity with primary HSCT team who would likely follow patient over the course of the transplant for continuity
Familiarity with inpatient social workers who follow patients closely
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