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. Author manuscript; available in PMC: 2020 May 3.
Published in final edited form as: Tuberculosis (Edinb). 2019 May 3;116 Suppl:S131–S137. doi: 10.1016/j.tube.2019.04.021

Figure 1. DNA from different M.tuberculosis phylogenetic lineages elicits differential inflammatory response in human macrophages.

Figure 1.

Dual THP-1 cells were stimulated for 24 hours with 100ng of DNA from several different phylogenetic lineages of Mtb. Response from IRF (A) or an NF-kB (B) reporters are shown. Pretreatment of cells with Vitamin D (gray bars) show increase the response to DNA from HN878 and virulent strain H37Rv (A). * p<0.05 Unpaired t test.