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Left panel: Mean cocaine intake (mg/kg) during the last 10 sessions of self-administration for all subjects prior to saline or NAC treatment (gray bar, n=6), and during the 10 sessions of saline (white bar, n=3) or NAC pretreatment (black bar, n=3). Right panel: Mean sessions required to meet extinction criteria. Extinction criteria were defined as a 1-hour session with fewer than 10 saline infusions earned. (p<.05)
