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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Tuberculosis (Edinb). 2019 Apr 26;116 Suppl:S118–S122. doi: 10.1016/j.tube.2019.04.019

Figure 1. Comparative gross pulmonary reactivity in models of TDM induced pathology.

Figure 1.

The lung weight index (LWI) was calculated post TDM administration, as a measure of gross pulmonary inflammation and cellular recruitment. Lungs from mice injected with TDM-IP (10 μg or 50 μg given IP), TDM-IV Acute (10 μg or 25 μg given IV), or TDM-IPIV Hypercoaculation (10 μg IP plus 10 μg IV) were assessed. Lungs were also isolated for comparison to naïve (non-injected) mice. At day 7 post final TDM administration, lungs were collected and weighed, and compared against weight of the mouse. Individual points represent unique animals. Results represent mean ± standard deviation, with similar data obtained from repeated experiments; 4–6 mice per group per experiment.