Skip to main content
. 2019 Jul 7;25(25):3256–3267. doi: 10.3748/wjg.v25.i25.3256

Table 3.

Factors associated with the values of liver stiffness measured by magnetic resonance elastography and two-dimensional shear wave elastography in univariate and multivariate linear regression analyses

Parameters Factors associated with liver stiffness values by MRE
Factors associated with liver stiffness values by 2D-SWE
Univariate P value Multivariate P value Univariate P value Multivariate P value
Sex, male/female -0.054 (-0.508, 0.401) 0.815 0.685 (-0.840, 2.210) 0.372
Age, yr 0.019 (-0.006, 0.044) 0.132 0.067 (-0.017, 0.151) 0.117
BMI, kg/m2 -0.048 (-0.114, 0.018) 0.149 -0.251 (-0.469, -0.034) 0.024 -0.186 (-0.366, -0.007) 0.042
AST, U/L 0.007 (-0.003, 0.017) 0.157 0.032 (-0.001, 0.065) 0.054
ALT, U/L 0.002 (-0.009, 0.013) 0.674 0.000 (-0.037, 0.037) 0.995
PLT counts, × 103/mm3 -0.007 (-0.012, -0.001) 0.014 0.001 (-0.002, 0.005) 0.530 -0.027 (-0.045, -0.009) 0.004 -0.012 (-0.029, 0.004) 0.136
PT, INR 1.312 (-1.595, 4.220) 0.370 8.658 (-0.971, 18.288) 0.077
Total bilirubin, mg/dL 0.331 (-0.140, 0.802) 0.165 0.098 (-1.517, 1.713) 0.904
Albumin, g/dL -0.540 (-1.510, 0.429) 0.270 -3.152 (-6.359, 0.055) 0.054
γ-GT, U/L 0.004 (-0.003, 0.011) 0.302 0.012 (-0.012, 0.036) 0.327
HBeAg status, +/- 0.166 (-0.282, 0.615) 0.461 1.052 (-0.445, 2.549) 0.165
HBV-DNA, log10 IU/mL -0.051 (-0.189, 0.086) 0.456 -0.076 (-0.541, 0.389) 0.745
Inflammatory grade 0.363 (0.153, 0.573) 0.001 0.105 (-0.031, 0.241) 0.129 0.903 (0.163, 1.644) 0.018 0.220 (-0.411, 0.852) 0.487
Fibrosis stage 0.626 (0.520, 0.732) < 0.001 0.609 (0.487, 0.731) < 0.001 1.616 (1.116, 2.116) < 0.001 1.276 (0.690, 1.863) < 0.001

MRE: Magnetic resonance elastography; 2D-SWE: Two-dimensional shear wave elastography; ALT: Alanine transaminase; AST: Aspartate transaminase; BMI: Body mass index; INR: International normalized ratio; PLT: Platelet; PT: Prothrombin time; γ-GT: Gamma-GT.