Table 3.
Factors associated with the values of liver stiffness measured by magnetic resonance elastography and two-dimensional shear wave elastography in univariate and multivariate linear regression analyses
| Parameters |
Factors associated with liver stiffness values by MRE |
Factors associated with liver stiffness values by 2D-SWE |
||||||
| Univariate | P value | Multivariate | P value | Univariate | P value | Multivariate | P value | |
| Sex, male/female | -0.054 (-0.508, 0.401) | 0.815 | 0.685 (-0.840, 2.210) | 0.372 | ||||
| Age, yr | 0.019 (-0.006, 0.044) | 0.132 | 0.067 (-0.017, 0.151) | 0.117 | ||||
| BMI, kg/m2 | -0.048 (-0.114, 0.018) | 0.149 | -0.251 (-0.469, -0.034) | 0.024 | -0.186 (-0.366, -0.007) | 0.042 | ||
| AST, U/L | 0.007 (-0.003, 0.017) | 0.157 | 0.032 (-0.001, 0.065) | 0.054 | ||||
| ALT, U/L | 0.002 (-0.009, 0.013) | 0.674 | 0.000 (-0.037, 0.037) | 0.995 | ||||
| PLT counts, × 103/mm3 | -0.007 (-0.012, -0.001) | 0.014 | 0.001 (-0.002, 0.005) | 0.530 | -0.027 (-0.045, -0.009) | 0.004 | -0.012 (-0.029, 0.004) | 0.136 |
| PT, INR | 1.312 (-1.595, 4.220) | 0.370 | 8.658 (-0.971, 18.288) | 0.077 | ||||
| Total bilirubin, mg/dL | 0.331 (-0.140, 0.802) | 0.165 | 0.098 (-1.517, 1.713) | 0.904 | ||||
| Albumin, g/dL | -0.540 (-1.510, 0.429) | 0.270 | -3.152 (-6.359, 0.055) | 0.054 | ||||
| γ-GT, U/L | 0.004 (-0.003, 0.011) | 0.302 | 0.012 (-0.012, 0.036) | 0.327 | ||||
| HBeAg status, +/- | 0.166 (-0.282, 0.615) | 0.461 | 1.052 (-0.445, 2.549) | 0.165 | ||||
| HBV-DNA, log10 IU/mL | -0.051 (-0.189, 0.086) | 0.456 | -0.076 (-0.541, 0.389) | 0.745 | ||||
| Inflammatory grade | 0.363 (0.153, 0.573) | 0.001 | 0.105 (-0.031, 0.241) | 0.129 | 0.903 (0.163, 1.644) | 0.018 | 0.220 (-0.411, 0.852) | 0.487 |
| Fibrosis stage | 0.626 (0.520, 0.732) | < 0.001 | 0.609 (0.487, 0.731) | < 0.001 | 1.616 (1.116, 2.116) | < 0.001 | 1.276 (0.690, 1.863) | < 0.001 |
MRE: Magnetic resonance elastography; 2D-SWE: Two-dimensional shear wave elastography; ALT: Alanine transaminase; AST: Aspartate transaminase; BMI: Body mass index; INR: International normalized ratio; PLT: Platelet; PT: Prothrombin time; γ-GT: Gamma-GT.