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. 2019 Jul 15;6:23. doi: 10.1186/s40580-019-0193-2

Table 1.

The stimuli-responsive release of drugs loaded on different nanocarriers

Stimuli Nanocarriers Drug Target References
pH Hybrid micelles Doxorubicin Breast cancer [72]
Mesoporous silica nanoparticles Doxorubicin Cervical cancer [73]
Dendrimers Doxorubicin Breast cancer [74]
Coordination polymer mesoporous silica nanoparticles Topotecan Cervical carcinoma [75]
Gold nanocages Doxorubicin Breast cancer [76]
Chitosan nanoparticles Tamoxifen Breast cancer [77]
Polymeric nanoparticles Cisplatin Ovarian cancer [78]
Titanium dioxide nanoparticles Daunorubicin Leukemia [79]
Redox Mesoporous silica nanoparticles Doxorubicin Glioblastoma [80]
Polymeric conjugates Doxorubicin Hepatocellular carcinoma [81]
Polymeric nanoparticles Camptothecin, doxorubicin Breast cancer [82]
Magnetic micelles Doxorubicin Hepatocarcinoma [83]
Chitosan nanoparticles Methotrexate Cervical cancer [84]
Gold nanoparticles Doxorubicin, methotrexate, 6-mercaptopurine Cervical, lung carcinoma [85]
Block copolymer nanoparticles Doxorubicin Lung cancer [86]
Magnetic field Magnetite nanoparticles Doxorubicin Multiple myelomas [87]
Magnetic nanoparticles Doxorubicin Liver cancer [88]
Iron oxide nanoparticles Homocamptothecin Squamous cell carcinoma [89]
PMAM-magnetite nanocrystallites Cisplatin Colon adenocarcinoma [90]
Superparamagnetic iron oxide nanoparticles Valrubicin Prostate cancer [91]
Magnetic nanoparticles Doxorubicin Cervical cancer [92]
Light Mesoporous bamboo charcoal nanoparticles Doxorubicin Breast cancer [93]
Telluride PEG co-block polymeric nanoparticles Cisplatin Breast cancer [94]
TiO2–iron oxide nanoparticles Artemisinin Breast cancer [95]
Chitosan-based nanocarrier Camptothecin Breast cancer [96]
Temperature Liposomes Tamoxifen, imatinib Breast cancer [97]
β-Cyclodextrin star polymer Paclitaxel, doxorubicin Liver cancer [98]
Polysaccharide based nanogels Doxorubicin Cervical cancer [99]

Specific nanocarriers, drug and targeted cancer have also been shown in the table