Table 2. Clinical difference between patients with IPF, other IIPs, and CVD-IP groups.
| Characteristics | IPF group (n=17) | Other IIPs group (n=28) | CVD-IP group (n=16) | P |
|---|---|---|---|---|
| Age, y | 75 [72–79.5] | 77.5 [73–82] | 76 [71.5–79.8] | 0.719 |
| Male sex | 14 (82%) | 23 (82%) | 8 (50%) | 0.042 |
| CCI | 2 [1–3] | 2 [1–4] | 2 [1.3–3] | 0.944 |
| Blood biomarkers | ||||
| PaO2/FiO2 ratio | 266 [204–290] | 259 [154–313] | 296 [148–343] | 0.744 |
| Serum LDH, U/L | 294 [259–425] | 302 [219–488] | 254 [231–337] | 0.322 |
| Serum SP-D, ng/mL | 266 [166–495] | 328 [146–430] | 220 [140–456] | 0.649 |
| Serum KL-6, U/mL | 995 [690–1,846] | 936 [572–2,480] | 884 [642–1,240] | 0.814 |
| HRCT scores | ||||
| Ground glass opacity | 10 [6.5–12] | 9 [6.3–12.8] | 10.5 [8–13.8] | 0.625 |
| Honeycomb | 7 [4–9] | 0 [0–3.8] | 3 [1.3–8.5] | <0.001 |
| 3-month morality rates, % | 35.3 | 35.7 | 18.8 | 0.460 |
Results are shown as medians with 25th–75th percentiles or n (%). CCI, Charlson comorbidity index; CVD-IP, collagen vascular diseases-related interstitial pneumonia; HRCT, high-resolution computed tomography; IIPs, idiopathic interstitial pneumonias; IPF, idiopathic pulmonary fibrosis; KL-6, Krebs von den Lungen; LDH, lactate dehydrogenase; PaO2/FiO2 ratio; partial pressure of oxygen in arterial blood/fraction of the inspiratory oxygen; SP-D, surfactant protein-D.