Table 3. Univariate analysis of dosimetric factors for overall survival.
Factors | Median (range) | Subcategory | HR (95% CI) | P value |
---|---|---|---|---|
MHD (Gy) | 13.1 (5.5–48.7) | ≥13.1 vs. <13.1 | 1.47 (0.83–2.63) | 0.19 |
MLD (Gy) | 19.1 (8.8–27.6) | ≥19.1 vs. <19.1 | 1.39 (0.79–2.50) | 0.29 |
Lung V5 (%) | 59.8 (20.6–82.5) | ≥59.8 vs. <59.8 | 1.87 (1.05–3.39) | 0.03 |
Lung V20 (%) | 32.0 (0–45.3) | ≥32.0 vs. <32.00 | 1.00 (0.56–1.77) | 0.99 |
Heart V5 (%) | 49.4 (0–100.0) | ≥49.4 vs. <49.4 | 1.90 (1.07–3.45) | 0.03 |
Heart V10 (%) | 39.4 (0–100.0) | ≥39.4 vs. <39.4 | 1.44 (0.82–2.59) | 0.21 |
Heart V15 (%) | 31.0 (0–99.8) | ≥31.0 vs. <31.0 | 1.48 (0.84–2.65) | 0.18 |
Heart V20 (%) | 22.7 (0–99.3) | ≥22.7 vs. <22.7 | 1.26 (0.71–2.24) | 0.43 |
Heart V25 (%) | 18.3 (0–98.8) | ≥18.3 vs. <18.3 | 1.22 (0.69–2.18) | 0.49 |
Heart V30 (%) | 15.6 (0–97.8) | ≥15.6 vs. <15.6 | 1.13 (0.64–2.01) | 0.66 |
Heart V35 (%) | 11.8 (0–76.6) | ≥11.8 vs. <11.8 | 1.30 (0.73–2.31) | 0.37 |
Heart V40 (%) | 9.1 (0–67.4) | ≥9.1 vs. <9.1 | 1.30 (0.74–2.32) | 0.37 |
Heart V45 (%) | 6.8 (0–61.3) | ≥6.8 vs. <6.8 | 1.34 (0.76–2.39) | 0.32 |
Heart V50 (%) | 5.3 (0–48.5) | ≥5.3 vs. <5.3 | 1.38 (0.78–2.47) | 0.27 |
Heart V55 (%) | 3.5 (0–38.7) | ≥3.5 vs. <3.5 | 1.47 (0.83–2.63) | 0.18 |
Heart V60 (%) | 1.9 (0–30.7) | ≥1.9 vs. <1.9 | 1.63 (0.92–2.96) | 0.09 |
MHD, mean heart dose; MLD, mean lung dose; HR, hazard ratio; CI, confidence interval.