Table 5. Univariate analysis of clinical factors for freedom from cardiac events.
| Factors | HR (95% CI) | P value |
|---|---|---|
| Age (≥67/<67 years) | 0.94 (0.29–3.01) | 0.92 |
| Gender (female/male) | 3.39 (1.00–15.42) | 0.05 |
| Race (White/non-White) | 0.75 (0.22–2.35) | 0.62 |
| Current smoker (yes/no) | 1.23 (0.39–4.15) | 0.73 |
| Cardiac comorbidity (yes/no) | 1.44 (0.38–4.62) | 0.56 |
| Lung comorbidity (yes/no) | 1.04 (0.33–3.33) | 0.95 |
| Diabetes mellitus (yes/no) | 0.80 (0.12–3.06) | 0.77 |
| Histology (SCLC/NSCLC) | 0.52 (0.03–2.72) | 0.50 |
| GTV (≥98.6 cm3/<98.6 cm3) | 1.88 (0.60–6.38) | 0.28 |
| PTV (≥495.3 cm3/<495.3 cm3) | 1.67 (0.53–5.65) | 0.38 |
| Radiotherapy technique (IMRT/3D CRT) | 1.84 (0.40–6.51) | 0.40 |
| ECOG performance status (1–2/0) | 1.53 (0.45–6.92) | 0.52 |
| Charlson comorbidity index (≥2/<2) | 0.58 (0.13–1.96) | 0.40 |
GTV, gross tumor volume; PTV, planning target volume; 3D CRT, three-dimensional conformal radiation therapy; IMRT, intensity-modulated radiation therapy; ECOG, Eastern Cooperative Oncology Group; Gy, gray.