Table 6. Univariate analysis of dosimetric factors for freedom from cardiac events.
Factor | Median (range) | Subcategory | HR (95% CI) | P value |
---|---|---|---|---|
MHD (Gy) | 13.1 (5.5–48.7) | ≥13.1 vs. <13.1 | 3.59 (1.06–16.30) | 0.04 |
Heart V5 (%) | 49.4 (0–100) | ≥49.4 vs. <49.4 | 6.69 (1.74–43.80) | 0.005 |
Heart V10 (%) | 39.4 (0–100.0) | ≥39.4 vs. <39.4 | 6.13 (1.61–40.00) | 0.008 |
Heart V15 (%) | 31.0 (0–99.8) | ≥31.0 vs. <31.0 | 6.08 (1.59–39.74) | 0.009 |
Heart V20 (%) | 22.7 (0–99.3) | ≥22.7 vs. <22.7 | 2.23 (0.70–8.40) | 0.18 |
Heart V25 (%) | 18.3 (0–98.8) | ≥18.3 vs. <18.3 | 3.26 (0.97–14.73) | 0.06 |
Heart V30 (%) | 15.6 (0–97.8) | ≥15.6 vs. <15.6 | 2.16 (0.68–8.14) | 0.20 |
Heart V35 (%) | 11.8 (0–76.6) | ≥11.8 vs. <11.8 | 2.29 (0.72–8.63) | 0.17 |
Heart V40 (%) | 9.1 (0–67.4) | ≥9.1 vs. <9.1 | 2.29 (0.72–8.63) | 0.17 |
Heart V45 (%) | 6.8 (0–61.3) | ≥6.8 vs. <6.88 | 1.50 (0.48–5.10) | 0.48 |
Heart V50 (%) | 5.3 (0–48.5) | ≥5.3 vs. <5.3 | 1.57 (0.50–5.33) | 0.44 |
Heart V55 (%) | 3.5 (0–38.7) | ≥3.5 vs. <3.5 | 1.67 (0.53–5.66) | 0.38 |
Heart V60 (%) | 1.9 (0–30.7) | ≥1.9 vs. <1.9 | 1.58 (0.50–5.34) | 0.43 |
MHD, mean heart dose; CI, confidence interval.