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Stabilities of Circular Permutants
| Variant | ΔGunf (kcal mol-1) | m (kcal mol-1 M-1) | Cm (M) |
|---|---|---|---|
| WT | 18.7 ± 1.2 | 9.0 ± 0.7 | 2.09 ± 0.03 |
| CP60 | 3.2 ± 0.4 | 1.9 ± 0.1 | 1.69 ± 0.09 |
| CP70 | 3.75 ± 0.05 | 2.7 ± 0.1 | 1.37 ± 0.03 |
| CP85 | 2.9 ± 0.2 | 1.9 ± 0.1 | 1.50 ± 0.09 |
| CP97 | 5.4 ± 0.3 | 4.0 ± 0.2 | 1.39 ± 0.01 |
| CP125 | 2.7 ± 0.1 | 2.0 ± 0.1 | 1.30 ± 0.01 |
All variants contain the F217A + D218S mutations. Errors are SDs of three independent measurements.
