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. 2019 Jul 5;26:101271. doi: 10.1016/j.redox.2019.101271

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© 2019 The Authors. Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Sulforaphane improves endothelium-dependent and H₂O₂-induced relaxations in human vascular tissue. Relaxation induced by acetylcholine (ACh, A-B) and H₂O₂ (C–D) in human penile resistance arteries (HPRA, A, C) and human corpus cavernosum (HCC, B, D) from patients with erectile dysfunction (ED) and from organ donors without erectile dysfunction (No ED). The influence of adding sulforaphane (SFN, 10 μM) on such responses in HPRA and HCC from ED patients is shown. Data are expressed as mean ± SEM of the percentage of maximal relaxation induced by papaverine (0.1 mM). n indicates the number of patients. ***p < 0.001 vs. No ED and ††† vs. ED by two-factors ANOVA test.