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Nox2-deficient neutrophils expressing high levels of PSGL-1 migrate to the alveolar space. (A) Peripheral blood neutrophil PSGL-1 expression at baseline and 2 h post zymosan injection, n ≥ 3. (B) Neutrophils from the BAL fluid of gp91phox−/y mice express more PSGL-1 following SIRS induction than neutrophils from WT mice, n ≥ 7. (C) PSGL-1 expression on neutrophils isolated from the lung digest 24 h after SIRS induction, n ≥ 4, *p < 0.05, ***p < 0.001.
