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. 2019 Jul 3;10:435. doi: 10.3389/fendo.2019.00435

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Copyright © 2019 Chioccarelli, Manfrevola, Ferraro, Sellitto, Cobellis, Migliaccio, Fasano, Pierantoni and Chianese.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A,B) Subcellular localization of sperm circRNAs (A) Separation of fraction A sperm into head- and tail-enriched fractions. Representative images of sperm showing intact sperm (left), along with head and tail-enriched fractions, as indicated. Scale bar 50 μm. (B) circRNAs up-regulated in B SPZ, differentially expressed in head and tail sperm; **p < 0.01. (C) CircRNAs down-regulated in B SPZ, differentially expressed in head and tail sperm; **p < 0.01.