Table 1.

Study Criteria for Precision

Log scale		Linear scale
MR value	SD criteria	%IS value∗	% CV
<3.5	≤0.21	>0.0316	≤50
3.5–4.25	≤0.29	0.0316–0.0056	≤75
>4.25	≤0.36	<0.0056	≤100

Data expressed as %IS are not normally distributed. However, MR values are normally distributed, facilitating statistical analyses. The %IS values above are shown to bridge to historical perspectives only. The estimated % CV for the %IS values were calculated to be equivalent to the SD criteria set for the MR space.

IS, international scale; MR, molecular response.

^∗Shown for reference; SD values of MR measurements formed the definitive acceptance criteria.