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. 2019 Jul 1;374(1779):20180215. doi: 10.1098/rstb.2018.0215

Table 1.

Pathologies linked with abnormal tissue mechanics and techniques used to probe them.

pathology technique type of samples reference
glioma shear rheology and compression mode human glioma cell lines Pogoda et al. [23]
glioblastoma atomic force microscopy human GBM tissue samples, mouse xenograft studies, primary human GBM cells Miroshnikova et al. [3]
glioblastoma atomic force microscopy, traction force microscopy, SAIM human GBM tissue samples, mouse xenograft studies with human GBM cells, primary human cells Barnes et al. [41]
glioblastoma multifrequency magnetic resonance elastography human brain parenchyma (non-invasive) of GBM patients Streitberger et al. [43]
traumatic brain injury a custom-built micro-indentation device P56 mouse brain tissue MacManus et al. [17]
neurodegenerative diseases (e.g. Parkinson's and Alzheimer's diseases) three-dimensional magnetic resonance elastography
ultrasound hyperechogenecity
human brain (non-invasive) for review, see Barnes et al. [42]