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In vitro stability of [125I]I-PIB-(HE)3-G3 and [125I]I-(HE)3-G3. Samples were incubated with 5000-fold molar excess of KI or in PBS (control) at room temperature for 3 h. Analysis was performed in duplicates. Data for each labeled protein was normalized to its initial radiochemical purity, taken as 100%.
| Test Solution | Normalized DARPin-Associated Activity, % | |
|---|---|---|
| [125I]I-PIB-(HE)3-G3 | [125I]I-(HE)3-G3 | |
| PBS (control) | 100 ± 0 | 99 ± 1 |
| 5000-fold KI | 99 ± 0 | 100 ± 0 |
