Table 1.
Molecular characteristics of the histone deacetylase inhibitor (HDACis) used.
Group | Compound | Chemical Structure | HDAC Specificity |
---|---|---|---|
Hydroxamate | Vorinostat (SAHA) |
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class I and II HDACs |
Trichostatin A (TSA) |
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class I and II HDACs | |
MC1568 |
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Class II HDACs | |
Benzamide | Entinostat (MS275) |
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HDAC 1 and HDAC 3 (class I HDACs members) |