AAP |
Nα-aroyl-N-aryl-phenylalaninamide |
AARS |
aminoacyl-tRNA synthase |
AcCys-GlcN-Ins |
acetylcysteine-glucosamine-inositol |
BDQ |
bedaquiline |
BTZ |
1,3-benzothiazin-4-one |
COX |
cyclooxygenase |
DARQ |
diarylquinoline |
Dnd |
deazaflavin (or cofactor F420)-dependent nitroreductase |
DPA |
decaprenylphosphoryl-β-d-arabinofuranose |
DPR |
decaprenylphosphoryl-β-d-ribofuranose |
DprE1 |
decaprenylphosphoryl-β-d-ribose-2′-oxidase |
DprE2 |
decaprenylphosphoryl-2-keto-β-d-erythro-pentose reductase |
DPX |
decaprenylphosphoryl-d-2′-keto-erythro-pentofuranose |
EGFR |
epidermal growth factor receptor |
ETC |
electron transport chain |
FGD1 |
coenzyme F420-dependent glucose-6-phosphate dehydrogenase |
GlcN-Ins |
glucosamine-inositol |
GyrA |
DNA gyrase domain A |
GyrB |
DNA gyrase domain B |
hERG |
human ether-a-go-go related gene |
HDT |
host-directed therapy |
IFN-γ |
interferon-γ |
IL |
interleukine |
LeuRS |
leucyl-tRNA synthase |
LTB4 |
leukotriene B4 |
LXA4 |
lipoxin A4 |
MbcA |
mycobactericidal antitoxin |
MbcT |
mycobactericidal toxin |
MDR |
multidrug resistant |
MmpL |
mycobacterial membrane protein large |
MmpS |
mycobacterial membrane protein small |
MSH |
mycothiol |
MSSM |
mycothione or mycothiol disulfide |
mTOR |
mammalian target of rapamycin |
Mtr |
mycothione reductase |
Mtb
|
Mycobacterium tuberculosis
|
NSAID |
non-steroidal anti-inflammatory drug |
PBTZ |
piperazine-containing BTZ |
PGE2 |
prostaglandin E2 |
RNS |
reactive nitrogen species |
ROS |
reactive oxygen species |
TA |
toxin–antitoxin |
TB |
tuberculosis |
TDR |
total drug resistant |
TDM |
trehalose dimycolate |
TMM |
trehalose monomycolate |
TNF |
tumor necrosis factor |
VEGF |
vascular endothelial growth factor |
WHO |
World Health Organization |
XDR |
Extensively drug resistant |
Zmp1 |
Zn2+ metalloprotease |