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. 2019 Jun 24;11(6):880. doi: 10.3390/cancers11060880

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Receiver operating characteristic (ROC) curve analysis used to identify the optimal cutoff point capable of detecting a tumor-derived sample. (A) Immunohistochemistry (IHC) intensity 1: the threshold identified was 1% p65BTK positivity. (B) IHC intensity 2: the threshold identified was 50% p65BTK positivity. (C) IHC intensity 3: the threshold identified was 80% p65BTK positivity.