Table 1.
Patients’ characteristics.
| Total (n = 117) |
Control Group (n = 89) |
POI Group (n = 28) |
p-Value (Control vs. POI) |
|
|---|---|---|---|---|
| Gender (Men/Women) | 88/29 | 68/21 | 20/8 | 0.595 |
| Age (years) | 64.0 ± 7.9 | 63.7 ± 7.5 | 65.0 ± 9.2 | 0.435 |
| Height (cm) | 163.4 ± 7.8 | 164.0 ± 7.5 | 161.5 ± 8.6 | 0.137 |
| Weight (kg) | 56.0 ± 8.9 | 56.0 ± 9.4 | 56.0 ± 7.5 | 1.000 |
| BMI (kg/m2) | 20.9 ± 2.7 | 20.8 ± 2.7 | 21.5 ± 2.7 | 0.203 |
| UBW (kg) | 60.2 ± 10.0 | 59.9 ± 9.5 | 61.1 ± 11.3 | 0.567 |
| Preoperative morbidities | ||||
| Mastication disorder | 10 (8.5%) | 7 (7.9%) | 3 (10.7%) | 0.638 |
| Dysphagia | 10 (8.5%) | 9 (10.1%) | 1 (3.6%) | 0.280 |
| Obstruction | 42 (35.9%) | 33 (37.1%) | 9 (32.1%) | 0.635 |
| Glucose intolerance | 30 (20.4) | 23 (25.8%) | 7 (25.0%) | 0.929 |
| Hypertension | 32 (27.4%) | 24 (27.0%) | 8 (28.6%) | 0.868 |
| Dyslipidemia | 8 (6.8%) | 5 (5.6%) | 3 (10.7%) | 0.351 |
| Tumor stage (0/IA/IB/IIA/IIB/IIIA/IIIB/IV) |
13/24/9/12/17/24/0/18 | 9/17/6/11/13/21/0/12 | 4/7/3/1/4/3/0/6 | 0.502 |
| Operative procedure (VATS/Open esophagectomy) |
76/41 | 56/33 | 20/8 | 0.411 |
| Esophageal reconstruction (Gastric conduit/Jejunal graft) |
110/7 | 84/5 | 26/2 | 0.767 |
| Postoperative complications | 77 (65.8%) | 51 (57.3%) | 26 (92.9%) | <0.001 |
| Postoperative morbidity | 61 (52.1%) | 39 (43.8%) | 22 (78.6%) | 0.001 |
| Postoperative meal start (POD) | 13.9 ± 13.6 | 10.1 ± 3.9 | 26.1 ± 23.7 | 0.002 |
| Postoperative meal interruption | 61 (52.1%) | 39 (43.8%) | 22 (78.6%) | 0.001 |
| Neoadjuvant therapy | 60 (51.3%) | 48 (53.9%) | 12 (42.9%) | 0.306 |
| Postoperative hospital stay (days) | 36.3 ± 26.3 | 26.7 ± 8.3 | 66.9 ± 38.4 | <0.001 |
| Postoperative chemotherapy within 1 year postoperatively * | 55 (47.0%) | 43 (48.3%) | 11 (39.3%) | 0.403 |
| Recurrence within 1 year postoperatively * | 37 (31.6%) | 26 (29.2%) | 10 (35.7%) | 0.516 |
| Postoperative mean survival time (years) | 4.5 ± 2.3 | 4.7 ± 2.2 | 3.5 ± 2.4 | 0.016 |
Data are expressed as the mean ± standard deviation or as the number of patients. Imputed data (*) are expressed as the mean ± standard error or as number of patients. Differences among two groups were analyzed using the unpaired t-test and chi-square test. BMI, body mass index; UBW, usual body weight; VATS, video-assisted thoracoscopic esophagectomy.