AML |
acute myeloid leukemia |
ATAC-seq |
assay for transposase-accessible chromatin with high throughput sequencing |
ATM |
ataxia telangiectasia mutated |
ATR |
ATM and RAD3-related |
ATRA |
all-trans retinoic acid |
BET-seq |
binding energy topography by sequencing |
BiFC |
bimolecular fluorescence complementation |
BMP |
bone morphogenic protein |
BRD4 |
bromodomain-related protein 4 |
CBP |
CREB-binding protein |
CDK9 |
cyclin-dependent kinase 9 |
CFU-G |
colony forming unit-granulocyte |
CFU-GM |
colony forming unit-granulocyte and monocyte |
CFU-M |
colony forming unit-monocyte |
ChIA-Pet |
chromatin interaction analysis by paired-end tag |
ChIP |
chromatine immune-precipitation CKII, casein kinase II |
CTCF |
CCCTC-binding factor |
CUT&RUN |
cleavage under targets and release using nuclease |
D-2-HG |
D-2-hydroxyglutarate |
DHODH |
dihydroorotate dehydrogenase |
DNase-Seq |
deoxyribonuclease I (DNase I)-hypersensitive site with high throughput sequencing |
DNMT |
DNA methyl transferase |
DOT1L |
disruptor of telomeric silencing 1-like protein |
Erg |
ETS-related gene |
EVI1 |
ecotopic viral integration site 1 |
FLT3 |
Fms-like tyrosine kinase 3 |
GFI1 |
growth factor independent 1 |
GSEA |
gene set enrichment analysis |
HAT |
histone acetyl-transferase |
HD |
homeodomain |
HDAC |
histone deacetylase |
HEXIM1 |
hexamethylene bisacetamide (HMBA) inducible protein 1 |
HMT |
histone methyltransferase |
HOXA9 |
homeobox A9 |
IDH |
isocitrate dehydrogenase |
IL1B |
interleukin 1 beta |
IRAK4 |
interleukin-1 receptor-associated kinase 4 |
KDM4C |
lysine-specific demethylase 4C |
LEDGF |
lens epithelium-derived growth factor |
Lmo2 |
LIM domain only 2 |
LSD1 |
lysine-specific demethylase 1 |
MAPK |
mitogen-activated protein kinase |
MEF2C |
myocyte enhancer factor 2C |
MEIS |
myeloid ecotropic viral integration site |
MLL |
mixed lineage leukemia |
MOF |
males absent on the first |
MPAL |
mixed-phenotype associated lineage leukemia |
Myb |
myeloblastosis gene |
NPM1 |
nucleophosmin 1 |
NSD1 |
nuclear receptor binding SET domain protein 1 |
NUP98 |
nucleoporin 98kDa |
OPN |
osteopontin |
PBX |
pre-B-cell leukemia transcription factor |
PKC |
protein kinase C |
PRC2 |
polycomb repressive complex 2 |
PRMT1 |
protein arginine N-methyltransferase 1 |
PTD |
partial tandem duplication |
pTEFb |
positive transcription elongation factor b |
RIME |
immunoprecipitation-coupled mass spectrometry of endogenous protein |
SAM |
S-adenosyl-methionine |
SELEX-seq |
systematic evolution of ligands by exponential enrichment followed by sequencing |
shRNA |
short non-coding RNA |
SMAD4 |
mothers against decapentaplegic homolog 4 |
TDG |
thymine DNA glycosylase |
TGFβ |
transforming growth factor beta |
WDR5 |
WD repeat protein 5 |
WT |
wild-type |
XPO-1 |
exportin-1 |
4C-seq |
circularized chromosome conformation capture with high throughput sequencing |