Figure 1.

Consumption of 4.5% aronia berry-supplemented diet mitigates wasting induced by T cell transfer colitis in mice. Splenic CD4⁺CD62L⁺ cells from C57BL/6J mice were transferred to Rag1^-/- mice. Mice consumed the AIN-93M diet (colitic control) or aronia-supplemented diet for five weeks. A third group of Rag1^-/- mice received splenic CD4⁺ cells, consumed AIN-93M diet, and served as the non-colitic control. (A) Body weight changes after T cell transfer, as mean percentage of initial body weight at transfer (n = 9–10/group). Data bearing different letters indicate significant within-week differences (p < 0.05). (B) Colon weight/length ratio (n = 9–10/group). (C) Tissue 2-deoxy-2-[¹⁸F]fluoro-d-glucose (FDG) uptakes at 1 h after intravenous injection of approximately 1.85 MBq of FDG (n = 4–6/group). Groups bearing different letters indicate significant differences between treatments (p < 0.05). Data are means ± SEMs.