Table 1.
Performance of MTBDRplus testing on sputum samples compared with culture-based drug susceptibility testing (DST) results. INH = isoniazid. MDR-TB = multidrug-resistant TB. NPV = negative predictive value. OFX = ofloxacin/moxifloxacin. PPV = positive predictive value. RIF = rifampin.
INH | RIF | OFX | MDR-TB | |||||
---|---|---|---|---|---|---|---|---|
% | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | |
Sensitivity | 88 | 80–94 | 69 | 39–91 | 83 | 36–100 | 80 | 44–97 |
Specificity | 97 | 94–99 | 100 | 98–100 | 97 | 94–99 | 100 | 98–100 |
PPV | 93 | 85–97 | 90 | 55–100 | 50 | 19–81 | 89 | 52–100 |
NPV | 96 | 92–98 | 99 | 97–100 | 99 | 97–100 | 99 | 98–100 |