Diversity of bioactive compound families with potential chemopreventive effects present in microalgae as a candidate for food supplements. The hydrophilic and lipophilic compounds’ groups are distinct. In order to provide a wide range of protective effects, the synergy between groups of molecules is required. This can be obtained with a two-step process (mixing the two hydro- and lipophilic extracts [37,38] or in one step process [39]. The combinations proposed will result in enhanced preventive activities action by blocking oxygen (ROS)/nitrogen (NOS) reactive species generation, inflammation, aberrant cell proliferation (such as cancers) and by potentiating the activities of the immune system (immunostimulatory functions). DMS: dimethylsulfide, ROS: oxygen reactive species; NOS: nitrogen reactive species; CDKs: cyclin-dependent-kinases.