Table 1.
Patient characteristics.
| Characteristic | Non-AKI (n = 20) | TAC–AKI (n = 6) | p-Value |
|---|---|---|---|
| Age (years) | 53.6 ± 11.3 | 47.4 ± 6.63 | 0.046 |
| Sex (male/female) | 6/14 | 0/6 | NS |
| Preoperative body weight (kg) | 60.0 ± 10.68 | 58.0 ± 10.13 | NS |
| Preoperative SCr (mg/dL) | 0.57 ± 0.15 | 0.57 ± 0.10 | NS |
| Preoperative BUN (mg/dL) | 10.4 ± 4.4 | 13.8 ± 8.7 | NS |
| Preoperative eGFR (mL/min/1.73 m2) | 103.9 ± 30.2 | 90.8 ± 19.4 | NS |
| MELD score | 15.5 ± 6.75 | 15.0 ± 6.45 | NS |
| Child–Pugh score | 10.2 ± 1.9 | 10.5 ± 2.4 | NS |
| GV (g) | 525.0 ± 106.6 | 416.2 ± 47.2 | 0.006 |
| GV/SLV (%) | 45.5 ± 7.4 | 37.2 ± 5.2 | 0.037 |
| GV/preoperative body weight (%) | 0.88 ± 0.15 | 0.73 ± 0.14 | NS |
| Primary disease (n) | NS | ||
| Primary biliary cirrhosis | 3 | 5 | |
| Hepatitis C virus-related liver cancer | 5 | 1 | |
| Hepatitis B virus | 3 | 0 | |
| Alcoholic cirrhosis | 5 | 0 | |
| Other | 4 | 0 | |
| Total tacrolimus dose between PODs 1 and 14 (mg) | 59.0 ± 20.6 | 50.64 ± 20.75 | NS |
| Blood tacrolimus between PODs 1 and 14 (ng/mL) | 10.71 ± 1.9 | 12.08 ± 1.00 | NS |
| ABO blood group match | NS | ||
| Identical/Compatible/Incompatible | 11/3/6 | 4/1/1 | |
The results are given as mean ± standard deviation. Statistical analysis was performed using the Mann–Whitney U test and chi-square test. Abbreviations: AKI, acute kidney injury; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate; GV, graft volume; MELD, Model for End-stage Liver Disease; NS, not significant; POD, postoperative day; SLV, standard liver volume; SCr, serum creatinine; TAC, tacrolimus.