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. 2019 Jun 5;11(6):1280. doi: 10.3390/nu11061280

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Global dose-response meta-analysis of the T2D–GI risk relation. The larger plot shows the mean increment in the log risk relation and 95% CI values. The 95% CI values were based on random effects analysis, the inner (black dashed) lines show the conventional CI values based on (τ² + σ²) whereas the outer (grey dashed) lines were based on an additional forecasting term, σ_f², so that the outer 95% CI was based on (τ² + σ² + σ_f²). Insert: Shows the corresponding unlogged RR (black, continuous), the lower 95% confidence limit when accounting for σ_f² (black dashed), and the corresponding log-linear prediction (red).