Table 2.

Expression of adenosine receptors in the cochlea after hearing onset in rodents. It includes only subtype and cell specific results. mRNA detection means PCR analysis and in situ hybridization, protein detection means Western-blot analysis and immunohistochemistry, while functional detection indicates pharmacological analysis in electrophysiological or Ca²⁺ imaging experiments. In case of mice and rats, results come from animals age P > 15. Results from guinea pigs are not separated by age as these animals have in utero hearing. IHC: Inner hair cell; OHC: Outer hair cell; SGN: Spiral ganglion neuron; IBC: Inner boarder cells; IPhC: Inner phalangeal cell; PC: Pillar cell; DC: Deiters’ cell; HC: Hensen’s cell; OSC: Outer sulcus cell; SV: Stria vascularis; RM: Reissner’s membrane.

Receptor Subtypes			Presence in the Cochlea (P > 15)
	Species	Detected	OHC	IHC	SGN	IBC & IPhC	PC	DC	HC	OSC	SV	RM
A1	rat	mRNA	[71]	[71]
		protein	[71]	[71,72,73]	[72,73]			[72,73]
		function	[71]	[71]
	mouse	function		[74]	[74]
	guinea pig	function	[75]	[75]	[75]
A2A	rat	protein		[72,73]	[72,73]			[72,73]
	mouse	protein			[76]						[76]
		function		[74]	[74]
A3	rat	protein	[72,73]	[72,73]	[72,73]		[73]	[72,73]	[72,73]	[72,73]