Table 2.
Correlations (Spearman’s R) between cortical and trabecular contents of Dickkopf- 1 (DKK1) and sclerostin (SOST), bone turn-over, bone mass, and strength.
| Characteristic | Cortical | Trabecular | ||
|---|---|---|---|---|
| DKK1 | SOST | DKK1 | SOST | |
| Age | −0.13 | −0.04 | −0.19 | −0.09 |
| Years since menopause | −0.23 | 0.00 | −0.30 | −0.19 |
| sPTH | −0.16 | −0.20 | −0.14 | −0.04 |
| sICTP | −0.10 | 0.07 | 0.00 | 0.09 |
| sAP | 0.22 | 0.03 | 0.20 | 0.08 |
| sOCN | 0.02 | 0.06 | 0.12 | 0.09 |
| OCN † | 0.28 * | 0.11 | 0.40 ** | 0.45 ** |
| Calcium † | 0.20 | 0.13 | −0.08 | −0.09 |
| BMD lumbar spine, n = 52 | 0.32 * | 0.10 | 0.33 * | 0.20 |
| BMD femoral neck, n = 50 | 0.41 ** | 0.21 | 0.17 | 0.10 |
| pQCT, n = 38 | 0.34 * | 0.51 ** | 0.11 | 0.28 |
| Fmax, n = 37 | 0.50 ** | 0.46 ** | 0.14 | 0.26 |
S, serum; PTH, parathyroid hormone; ICTP, carboxyterminal telopeptide of type I collagen; OCN, osteocalcin; BMD, bone mineral density; pQCT, apparent trabecular bone volumetric density; Fmax, compressive strength. * p < 0.05, ** p < 0.01. † Bone matrix levels.