Table 1. Cytotoxicity (IC₅₀, nM) of Ipomoeassin F, Cotransin (CT8), and Probes 3, 5, and 7–15^a.

	cell line
	MDA-MB-231b	MCF7	MCF-10A	HCT116b,c
ipomoeassin F	6.3	36.4	5.3	8
CT8	–d	–	–	243
3	6.3	22.2	9.6	–
5	29.5	187.4	21.7	–
7	7.0	19.8	5.1	–
8	>25,000	>25,000	–	2832
9	>25,000	>25,000	–	–
10	8.9	172.2	11.3	–
11	2.8	21.1	2.0	–
12	253.4	172.2	133.8	–
14	98018	256018	–	1874
15	42918	47718	–	480

^aThe data were obtained from at least two independent experiments, and the standard errors are within 20%.

^bSee Figure S1 for IC₅₀ curves.

^cAssayed separately.

^d“–” indicates “not determined”.