Table 1.
All participants |
AN subtypes |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Healthy subjects |
Patients with AN |
p value (vs. healthy subjects) |
Patients with ANR |
p value (vs. healthy subjects) |
Patients with ANBP |
p value (vs. healthy subjects) |
p value (vs. patients with ANR) |
|||||
(n = 20) |
(n = 22) |
(n = 12) |
(n = 10) |
|||||||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||||
Demographic profiles | ||||||||||||
Age, years | 22.4 | 3.2 | 24.8 | 6.0 | 0.10 | 24.3 | 6.0 | 0.30 | 25.4 | 6.2 | 0.17 | 0.69 |
Current BMI, kg/m2 | 20.5 | 2.2 | 14.4 | 1.4 | < 0.001 | 13.8 | 1.3 | < 0.001 | 15.2 | 1.3 | < 0.001 | < 0.05 |
Disease duration, years | na | na | 5.2 | 5.7 | na | 4.2 | 5.0 | na | 6.4 | 6.5 | na | 0.37 |
Length of amenorrhea, years | na | na | 3.2 | 3.9 | na | 3.3 | 4.6 | na | 3.2 | 3.1 | na | 0.92 |
Education history, years | 14.8 | 1.7 | 13.0 | 1.9 | < 0.005 | 12.9 | 1.6 | < 0.005 | 13.2 | 2.3 | < 0.05 | 0.74 |
17β estradiol, ng/l | 83.0 | 29.5 | 90.8 | 20.2 | 0.35 | 92.8 | 14.5 | 0.31 | 87.9 | 26.9 | 0.70 | 0.61 |
Psychological profiles | ||||||||||||
Eating disorder inventory-2 | 27.7 | 20.6 | 115.5 | 70.3 | < 0.001 | 99.6 | 52.5 | < 0.001 | 134.7 | 86.2 | < 0.005 | 0.25 |
Beck depression inventory-II | 4.9 | 4.2 | 26.1 | 13.7 | < 0.001 | 21.4 | 10.5 | < 0.001 | 31.7 | 15.4 | < 0.001 | 0.08 |
State anxiety score of STAI | 34.6 | 5.1 | 54.3 | 11.1 | < 0.001 | 54.8 | 10.9 | < 0.001 | 53.8 | 12.0 | < 0.001 | 0.83 |
Trait anxiety score of STAI | 40.9 | 8.7 | 58.7 | 14.1 | < 0.001 | 55.7 | 14.3 | < 0.001 | 62.4 | 13.6 | < 0.001 | 0.28 |
Y-BOCS | 17.5 | 2.8 | 13.3 | 11.6 | < 0.001 | 9.8 | 10.8 | < 0.05 | 17.4 | 11.7 | < 0.005 | 0.13 |
Cognitive profiles | ||||||||||||
RCPM | 34.5 | 1.7 | 34.6 | 1.5 | 0.78 | 34.5 | 1.6 | 0.83 | 34.6 | 1.4 | 0.81 | 0.98 |
Stroop interference | 5.4 | 6.9 | 6.1 | 8.9 | 0.77 | 7.5 | 6.0 | 0.40 | 4.6 | 11.7 | 0.80 | 0.46 |
Net total score of Iowa gambling task | 17.9 | 19.4 | −3.6 | 22.3 | < 0.005 | −1.8 | 24.0 | < 0.05 | −5.8 | 21.1 | < 0.05 | 0.69 |
Reaction time in dot-probe task, milliseconds | 408.7 | 55.2 | 470.6 | 59.9 | < 0.005 | 452.8 | 58.5 | < 0.05 | 491.9 | 57.1 | < 0.001 | 0.13 |
Abbreviations: AN, anorexia nervosa; ANR, restricting-type AN; ANBP, binge-eating/purging-type AN; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); STAI, state-trait anxiety inventory; Y-BOCS, Yale-Brown Obsessive Compulsive Scale; RCPM, Raven's colored progressive matrices; na, not applicable.