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. 2019 Jun 3;11(6):767. doi: 10.3390/cancers11060767

Figure 2.

Figure 2

Upregulation of SSTR2 at the transcriptional level in H727, a pulmonary carcinoid cell line. Using two concentrations of five different histone deacetylase (HDAC) inhibitors, there is an increase in SSTR2 mRNA expression. There was a statistically significant increase after treatment with 6 nM romidepsin (FK228), 3 µM suberoylanilide hydroxamic acid (SAHA), 1 mM and 4 mM valproic acid (VPA), 2 nM and 6 nM thailandepsin A (TDP-A) and 3 µM AB3.